Neutrophil Kinetics in Acute Infection*
نویسندگان
چکیده
منابع مشابه
Neutrophil kinetics in acute infection.
Neutrophil kinetics of acute experimental infection were studied with diisopropylfluorophosphate-(32)P labeling in 31 dogs inoculated intrabronchially with pneumococci. In vitro neutrophil labeling indicated a rapid transit time through the blood in early infections, with an elevated marginal granulocyte pool sometimes preceding an elevation of the circulating granulocyte pool. 13 hr after infe...
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Quantitative studies of bone marrow neutrophil pool sizes and production rates and of blood neutrophil kinetics were performed in 16 patients with chronic neutropenia without splenomegaly. Marrow netrophil cellularity was determined from a ferrokinetic estimate of marrow normoblasts and from neutrophil-erythroid ratios determined from marrow sections. Postmitotic pool turnover was derived from ...
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Using patient data from a unique single source outbreak of hepatitis B virus (HBV) infection, we have characterized the kinetics of acute HBV infection by monitoring viral turnover in the serum during the late incubation and clinical phases of the disease in humans. HBV replicates rapidly with minimally estimated doubling times ranging between 2.2 and 5.8 d (mean 3.7 +/- 1.5 d). After a peak vi...
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The etiology of acute diarrhea was studied in 915 children under 5 years of age between March 1986 and August 1987, in 7 hospitals in Tehran. 65 healthy children in similar age groups served as controls. Rotavirus was found in 25% of the patients and 1.5% of controls with the highest detection rate occurring in the 7-24 month age group (28%) and declining beyond 25 months of age (5%). The ...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1967
ISSN: 0021-9738
DOI: 10.1172/jci105684